Ceftriaxone and Sulbactam Injection

Ceftriaxone and Sulbactam Injection come with the brand name “TECEF-S-1.5” and belong to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Ceftriaxone and Sulbactam Injection is a combination of two medicines: Ceftriaxone and Sulbactam. Ceftriaxone is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Sulbactam inhibits the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (ceftriaxone).

Medical Benefits

• Ceftriaxone is a cephalosporin antibiotic, whereas Sulbactam is a beta-lactamase inhibitor.
• This injection has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria.
• It makes the drug effective in multiple serious bacterial infections, including infections of the bloodstream (septicemia), bones (osteomyelitis), the heart valves (endocarditis), the membranes protecting the brain (meningitis), acute bacterial otitis media (infection of the middle ear) and the lining of the abdomen (peritonitis) and to prevent and treat infections following surgeries.

Directions for Use

• Ceftriaxone and Sulbactam Injection will be administered by a healthcare professional.
• Do not self-administer.

Storage

• Store in a cool and dry place.
• Keep it away from sunlight.
• Keep out of the reach of children.

Precautions

• Avoid alcoholic beverages with this composition as they can make you dehydrated and may affect your sleep.
• Ceftriaxone and Sulbactam Injection should be used with caution if you have a history of renal function impairment due to the increased risk of severe side effects.4
• It is not recommended for use in breastfeeding/pregnancy unless absolutely necessary. Inform your doctor if you are breastfeeding or pregnant.

Side Effects

• Diarrhoea
• Anaphylaxis
• Elevated liver enzymes
• Nausea
• Vomiting

Frequently Asked Questions (FAQs)

What are the common side effects of this injection?

Common side effects of these injections are pain and swelling at the injection site, skin rash, diarrhoea, nausea, vomiting and black/tarry stools. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, inform your doctor immediately.

In which conditions should I avoid taking it?

This medication should be avoided in conditions like gastrointestinal diseases, liver diseases, kidney diseases, seizure disorders, bleeding disorders, antibiotic resistance and bleeding disorders.

Can I stop this injection suddenly?

Do not stop taking it suddenly because your symptoms may improve before the infection is completely cured. Complete the full course of treatment even if you feel better.

Can I take this injection if I am allergic to penicillin?

People allergic to penicillin should not take it as they may develop cross-sensitivity (sensitivity to drugs with similar structures). This composition contains ceftriaxone, which has a similar structure to that of penicillin.